CBD is another cannabinoid that has been used by many patients lately. It is also present in raw cannabis as its Acid form, CBD-Acid. CBD-Acid also undergoes decarboxylation, but in that case both of the molecules are non-psychoactive; they don’t get you high.

CBD is a non-psychoactive cannabinoid that brings relief to anxiety, insomnia, psychosis, and certain forms of epilepsy.

One interesting study done with CBD on 8 patients suffering with epileptic convulsions showed that 200-300mg of CBD per day kept 4 of the patients almost free of convulsions for up to 4 months and reduced convulsions for 3 others (one patient was unaffected). The study also showed that there were no signs of toxicity with CBD even in large doses of up to 700mg per day,

In phase 1 of the study, 3 mg/kg daily of cannabidiol (CBD) was given for 30 days to 8 health human volunteers. Another 8 volunteers received the same number of identical capsules containing glucose as placebo in a double-blind setting. Neurological and physical examinations, blood and urine analysis, ECG and EEG were performed at weekly intervals. In phase 2 of the study, 15 patients suffering from secondary generalized epilepsy with temporal focus were randomly divided into two groups. Each patient received, in a double-blind procedure, 200-300 mg daily of CBD or placebo. The drugs were administered for along as 4 1/2 months. Clinical and laboratory examinations, EEG and ECG were performed at 15- or 30-day intervals. Throughout the experiment the patients continued to take the anti epileptic drugs prescribed before the experiment, although these drugs no longer controlled the signs of the disease. All patients and volunteers tolerated CBD very well and no signs of toxicity or serious side effects were detected on examination. 4 of the 8 CBD subjects remained almost free of convulsive crises throughout the experiment and 3 other patients demonstrated partial improvement in their clinical condition. CBD was ineffective in 1 patient. The clinical condition of 7 placebo patients remained unchanged whereas the condition of 1 patient clearly improved. The potential use of CBD as an anti epileptic drug and its possible potentiating effect on other anti epileptic drugs are discussed.